The Best Vitamin B12 Supplement

LAST UPDATED: August 28, 2018 by Sasha deBeausset
If you have a vitamin B12 deficiency or you just want to increase your B12 intake, supplements may be a viable option for you to consider. There are so many different vitamin B12 supplements on the market that it can be overwhelming to find the best option. Fortunately,to help you find the best B12 supplements on the market, we researched and reviewed the top five options.  
Nu U Nutrition Vitamin B12 Methylcobalamin 1000mcg Vitamin B12 Methylcobalamin by Nutribioticals Vitamin B12 Methylcobalamin Tablets by Puretality Vegan Vitamin B12 Methylcobalamin by Vegavero Vegan Vitamin B12 Methylcobalamin by Innopure

The Best B12 Supplements

Nu U Nutrition made these vitamin B12 supplements with maximum potency and increased absorption.  Methylocobalmin is one of the most bio-available forms of vitamin B12.  To maximise the absorption, place a tablet under your tongue until it melts.

Letting the tablet melt under your tongue ensures that it enters straight into the bloodstream, which increases the absorption by up to 25%.  If you prefer, you can swallow these tablets as well.

Unlike other B12 supplements that are manufactured in Asia and the United States, Nu U Nutrition manufactures these Methylcobalamin 1000mcg vitamin B12 supplements in the UK.  Local manufacturing ensures that your product meets one of the highest quality standards in the world.

Their formula doesn’t contain any milk, lactose, gluten, yeast, wheat or soya.  If you’re a vegetarian that has trouble finding supplements that meet your dietary restrictions, these supplements are safe for you to consume.

Some supplements require you to reorder on a monthly basis.  However, Nu U Nutrition packed enough tablets in this container to last you for six months.  Simply take one tablet per day under the tongue or by swallowing.

These supplements can increase your energy and mental alertness.  The taste is fruity and fresh, which is refreshing compared to other supplements that have an unsavoury aftertaste.


  • Manufactured in the UK.
  • Increases energy and mental alertness.
  • Dissolve under tongue for 25% higher absorption.
  • Supply lasts for six months.
  • Suitable for vegetarians.


  • May take several weeks before you notice results.
  • Takes some time to dissolve under tongue.

Nutribioticals is a global leader for British vitamin B12 products.  Their facility is located in the UK, and everything is manufactured locally.  Local manufacturing ensures that you get the freshest and highest quality products.

The Nutribioticals vitamin B12 supplements are suitable for vegetarians.  These supplements do not contain any yeast, lactose, soya, or wheat.  They only use 100% pure Methylcobalamin in their formula.  Nutribioticals does not add any artificial flavours or additives to the product.

These supplements can help boost your energy levels and improve your brain function.  You’ll feel less tired throughout the day.  Furthermore, these B12 supplements help boost and maintain your immune system.  The supplements are non-toxic, water soluble, and completely safe for consumption.

Nutribioticals offers a 100% money back guarantee.  If you are not satisfied with your purchase for any reason, just contact the manufacturer to get your refund.

You can consume these supplements by swallowing them.  However, if you place them under your tongue, then you can increase the absorption into your bloodstream to maximise the results.

The European Food Safety Authority (EFSA) approved the claims that the Nutribioticals vitamin B12 supplements can help immune function, metabolism, neurological functions, psychological functions, tiredness and fatigue.


  • Suitable for vegetarians.
  • 100% pure Methylcobalamin
  • Money back guarantee.
  • Boosts energy levels.
  • Improves brain function.


  • May take several weeks to notice results.
  • Recommended dosage is low.

The sublingual vitamin B12 Methylcobalamin 1000mcg supplements from Puretality increases the absorption into your bloodstream by up to 25%.

They use vegetarian vitamin B12 supplements from the active form of Methylcobalamin.  It results in normal function of the immune system.  You’ll also benefit from normal nervous system function, physiological function, and red blood cell formation.  If you have a vitamin B12 deficiency, these supplements can help get all of your levels back to normal.

If you’re not satisfied with your purchase from Puretality, just contact them and receive a 100% money back guarantee.  They are confident with their product and stand by the results.  They manufacture everything in the UK, so you know that the factory practices safe hygiene standards.

Some brands only offer 60 tablets in a bottle.  However, Puretality gives you 180 tablets to last you for six months.

These tablets are orange flavoured, so they are refreshing and tasty as they dissolve under your tongue.  Some other companies produce products that have a bad after taste, but Puretality understands that you may have a sensitive palate.


  • Sublingual tablets increase absorption into the bloodstream.
  • Six month supply.
  • Orange flavour.
  • Manufactured in the UK.
  • Improve immune system function.


  • May experience some itching as a side effect.
  • Sweet taste.

Vegavero made these vitamin B12 supplements with the vegan diet in mind.  These tablets do not contain any gelatin, lactose, GMO, gluten, additives, artificial flavours, and artificial colours.

Unlike other vitamin B12 supplements that only contain Methylcobalamin, the Vegavero formula also has vitamin B6 and folic acid.  Both of these additional supplements are linked to the dependent processes of B12 in the metabolic process.

Methylcobalamin is the most bioavailable form of vitamin B12.  That’s why Vegavero used this form of the vitamin to manufacture these supplements.  It’s a fast absorbing formula so you can get vitamins into your bloodstream at an efficient rate.

Vegavero is a family run business.  Their local operation gives them the opportunity to oversee the manufacturing process.  They work with a team of doctors, pharmacists, and nutrition specialists to develop the most advanced supplements on the market.

If you’re not satisfied with your purchase, Vegavero will refund 100% of your money, guaranteed.  Simply contact the company directly and let them know if you had any problems.

These supplements can help boost your energy levels, brain health, and improve healthy digestion.  Your overall mood will improve as well.  Their B12 supplements help you properly metabolise proteins, which promotes healthy hair, skin, and nails.


  • Vegan formula
  • Boosts energy levels, mood, and brain health
  • Contains vitamin B6 and folic acid
  • Money back guarantee
  • Promotes healthy skin, hair, and nails


  • Some customers had trouble reading instructions.
  • Expires in one year.

Innopure created a four-month supply of vitamin B12 supplements that are easy for you to swallow.  The formula supports energy production and contributes to the normal function of your nervous system and immune system.  It also helps contribute to normal cell division and the formation of red blood cells.

You may feel less tired throughout the day if you start using the vitamin B12 supplements from Innopure.  There are no artificial flavours or artificial colours in the formula.  The ingredients are safe for vegans and vegetarians.  The supplements are free of gluten, soya, wheat, porcine, yeast, lactose, starch, milk and sweeteners.

The Vegetarian Society and Vegan Society approved these ingredients.

Innopure manufactures their supplements in the UK, so everything is fresh.  Their process meets the high quality standards controlled by the GMP guidelines.

These supplements work best when combined with a healthy lifestyle and a well-balanced diet.  If you do not practice healthy lifestyle habits, you may not gain any of the benefits from these vitamin B12 supplements.


  • Approved by the Vegetarian Society and Vegan Society.
  • Does not contain any artificial flavours or artificial colours
  • Supply will last you for four months.
  • Improves normal function of nervous system and immune system.
  • Manufactured in the UK.


  • Won’t work without healthy lifestyle practices and a well-balanced diet.
  • May take several weeks to experience benefits.

How to Choose the Best B12 Supplement

There are two types of vitamin B12 supplements. The first kind is a standard pill or tablet that you swallow. You can also find vitamin B12 supplements that dissolve under your tongue. These are referred to as sublingual supplements. Sublingual supplements enter your bloodstream through the mucosal membrane in your mouth. They don’t have to pass through your gastrointestinal tract to enter your blood. When the B12 supplements absorb into your bloodstream, they absorb into your system at a higher rate. (Healthy Eating) With that in mind, you can still swallow sublingual supplements. They just won’t have the same absorption effect. When shopping for vitamin B12 supplements, you should decide if you want to swallow your supplements or let them dissolve under your tongue. That way you can buy a product that tailors towards your preferences. You should also consider how often you want to reorder your vitamin B12 supplements. The amount of tablets per container drastically varies between each brand. If you don’t want to order too often, look for a company that provides enough to last you for six months. Other brands have supplies that only last for a couple of months.

What Are the Benefits of Using B12 Supplements?

B12 supplements offer a wide range of health benefits. It can help slow aging, help prevent memory loss and Alzheimer’s disease. It also boosts your energy, mental function, immune system, concentration, and mood. Vitamin B12 can reduce the risk of clogged arteries after surgery and help prevent heart disease, nerve damage, diabetes, and sleep disorders. (WebMD)

Things to Look For That Differentiate B12 Supplements

Look for vitamin B12 supplements that contain Methylcobalamin. There are different forms of vitamin B12, but Methylcobalamin is the most bioavailable form. (Livestrong) Methylcobalamin increases your available physical energy, encourages detox, supports brain health and nerve health (Global Healing Centre). Look for vitamin B12 supplements that were manufactured locally. Products that were made locally have to meet certain health and hygiene standards. Also, look for supplements with a money back guarantee. If the manufacturer is willing to stand behind their product, it means they are confident that you will be satisfied with the results.

Controversy Surrounding B12 Supplements

Like most supplements, there are certain side effects associated with vitamin B12. It’s common for people to experience headaches, itching, swelling, nerves, and anxiety in the short term. Some long term and serious side effects include blood clots in the arms and legs, low potassium in the blood, heart failure, fluid in the lungs, and a swelling tongue. (Everyday Health)

Prerequisites to Using B12 Supplements

Vitamin B12 supplements are only effective if you combine them with a healthy lifestyle and a well-balanced diet. You won’t get the health benefits if you continue to live an unhealthy lifestyle. You should speak to your doctor before starting a supplement routine that’s long term. If you have a vitamin B12 deficiency, you may want to discover the underlying cause of the deficiency. The use of vitamin B12 supplements are not intended for people under the age of 18.


If you purchase one of the B12 supplements that we reviewed above, you will most likely be satisfied with your decision.  All of these products give you a wide range of health benefits associated with B12 supplements.  They can also help restore normal body functions if you have a B12 deficiency. However, the Vitamin B12 Methylcobalamin 1000mcg 180 Tablets (6 Month's Supply) by Nu U Nutrition is the top choice on our list.  The Nu U Nutrition formula meets all of the criteria that we outlined earlier for the things to look for when purchasing a vitamin B12 supplement. You have two options with these tablets.  You can either swallow them or let them dissolve under your tongue.  If you dissolve the tablets under our tongue they absorb into your bloodstream at a 25% higher rate. The formula is suitable for vegetarians, and it’s manufactured in the UK.  Nu U Nutrition provides enough tablets to last you for six months.  That way you won’t have to constantly order your supplements every month or two.  

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